Cochrane reviews are the principal product of the Collaboration and are published electronically in successive issues of The Cochrane Database of Systematic Reviews. Preparation and maintenance of Cochrane reviews is the responsibility of 49 international collaborative review groups (CRGs), which are structured to cover all of areas of health care. The members of these groups are researchers, health care professionals, consumers, and others. Members of collaborative review groups have access to training materials and software developed by the Collaboration and to training workshops organised by Cochrane centers and others.

Every group has an editorial base with a Coordinating Editor and Coordiantor who organise and manage the day-to-day activities of the group.

Each CRG has a "module" withing the Cochanre Library where it defines its scope (ie, the types of health problems it will address in its reviews; who has responsibility for planning, coordinating and monitoring the group's work (a coordinating editor, supported by an editorial team); how the group will identify and assemble in a specialised register the studies relevant to its declared scope; and who will take responsibility for preparing and maintaining which reviews.

List of Cochrane Review Groups